Use of Ganz und Ganzen

When to use Ganz und Ganzen . Which is the diference ?

I don´t the diference to use Ganz und Ganzen

Someone can help me with this question?  About When use Ganz and Ganzen.

The tutors are very slow to answer so I will have a go.

I think you are asking when ganz needs an ending and when it doesn't.
This is really a general question about adjectives and adverbs.
Adjectives need an ending but when the same word is used as an adverb it doesn't.

So if ganz is being used to directly describe a noun (as an adjective), it needs an ending.
The ending must agree in number gender and case with the noun.
There is a web page on adjective endings here:
https://www.learn-german-smarter.com/learn-german-adjective-endings/

e.g. Wir spielen den ganzen Tag.
Tag is masculine singular and it is the object of the sentence so  ganz should have the masculine accusative singular ending which is "en".
Examples where ganz doesn't need an ending as it is not describing a noun:

Basic grammar. Ganzen Tag is an adjective; ganz gut is not.