Brian: I think in your second example, "¿Me puede decir la hora?", me is an object pronoun, which in Spanish is placed in front of the conjugated verb. The third question, "¿En que le puedo ayudar?" is the same construction: le is the object pronoun for he, she, or it, and goes in front of the verb.
Alternatively, the pronoun can be placed at the end of an infinitive, so the second sentence could be constructed as, "¿Puede decirme la hora?" and the third as "¿En que puedo ayudarle?"
It is not just questions where the object pronoun precedes the verb; statements do the same thing: "Manuel lo tiene." (Manuel has it.)
The same holds true with reflexive pronouns, such as "Me gusta la comida." (The food pleases me.)
If I have misled you I hope someone corrects me...